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If you want to create an unusual and unique piece of gemstone jewelry, you can consider either design or materials to make it stand out in a crowd. For example, a short, single-strand necklace with a clasp on the end would typically call for carefully arranged gemstones descending in size. Tweak this design and alternate your large and small beads with a fabulous center pendant. Or group gemstones of a more dominant color together and create a fading effect. An unusual material to use in your jewelry making would be Carnelian gemstones. Carnelian gemstones are bright red-orange to deep, brown-orange chalcedony. Small carnelian gem stone beads will appear more translucent; large beads will appear more opaque. They look terrific on a unique and bold piece of bead jewelry.