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Silk pearl thread is your best choice for knotting because it's soft, pliable, and won't harm your pearls. That's why most beaders choose this type of thread to pair with the queen of gems. Keep enough spare silk pearl thread on hand to repair a pearl strand if should break. It's also a good idea to restring your pearls about once a year if you like to wear them often - spare thread is a must for that, too.